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Epstein Barr Virus Exploits Genetic Susceptibility to Increase Multiple Sclerosis Risk

21 Oct 2021

Abstract excerpt

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) for which both genetic and environmental risk factors have been identified. The strongest synergy among them exists between the MHC class II haplotype and infection with the Epstein Barr virus (EBV), especially symptomatic primary EBV infection (infectious mononucleosis) and elevated EBV-specific antibodies. In this review, we...

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PMID: 34835317
DOI: 10.3390/microorganisms9112191

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