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Article

Lack of developmental redundancy between Unc45 proteins in zebrafish muscle development.

PloS one - 1 Jan 2012

Comyn Sophie A, Pilgrim David

Abstract excerpt

Since the majority of protein-coding genes in vertebrates have intra-genomic homologues, it has been difficult to eliminate the potential of functional redundancy from analyses of mutant phenotypes, whether produced by genetic lesion or transient knockdown. Further complicating these analyses, not all gene products have activities that can be assayed in vitro, where the efficiency of the various family members...

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Identifiers

PMID: 23144999
DOI: 10.1371/journal.pone.0048861
PMCID: PMC3492250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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