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Article

Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos.

The Journal of cell biology - 3 May 2010

Etard Christelle, Roostalu Urmas, Strähle Uwe

Abstract excerpt

The chaperones Unc45b and Hsp90a are essential for folding of myosin in organisms ranging from worms to humans. We show here that zebrafish Unc45b, but not Hsp90a, binds to the putative cytidine deaminase Apobec2 (Apo2) in an interaction that requires the Unc45/Cro1p/She4p-related (UCS) and central domains of Unc45b. Morpholino oligonucleotide-mediated knockdown of the two related proteins Apo2a and Apo2b causes...

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Share to Cytidine Deaminase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20440001
DOI: 10.1083/jcb.200912125
PMCID: PMC2867308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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