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Article

The unc-45 gene of Caenorhabditis elegans is an essential muscle-affecting gene with maternal expression.

Genetics - 1 Oct 1990

Venolia L, Waterston R H

Abstract excerpt

We have isolated three novel alleles of the unc-45 locus in C. elegans, that are recessive lethals. Two of these alleles, when homozygous, result in a nearly total loss of muscle contraction with a concomitant arrest of development and a displacement of muscle cells. The third allele is similar, but showed maternal rescue by a wild-type allele. All previously identified unc-45 alleles were temperature sensitive...

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Identifiers

PMID: 2245914
DOI: 10.1093/genetics/126.2.345
PMCID: PMC1204189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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