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Article

Purification, crystallization and preliminary crystallographic analysis of the full-length cystathionine β-synthase from Apis mellifera.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Nov 2012

Oyenarte Iker, Majtan Tomas, Ereño June, Corral-Rodríguez María Angeles, Klaudiny Jaroslav, Majtan Juraj, Kraus Jan P, Martínez-Cruz Luis Alfonso

Abstract excerpt

Cystathionine β-synthase (CBS) is a pyridoxal-5'-phosphate-dependent enzyme that catalyzes the first step of the transsulfuration pathway, namely the condensation of serine with homocysteine to form cystathionine. Mutations in the CBS gene are the single most common cause of hereditary homocystinuria, a multisystemic disease affecting to various extents the vasculature, connective tissues and central nervous...

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Identifiers

PMID: 23143241
DOI: 10.1107/S1744309112038638
PMCID: PMC3515373

Genes

CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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