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Article

Structural insights into mutations of cystathionine beta-synthase.

Biochimica et biophysica acta - 11 Apr 2003

Meier Markus, Oliveriusova Jana, Kraus Jan P, Burkhard Peter

Abstract excerpt

Cystathionine beta-synthase (CBS) is a unique heme-containing enzyme that catalyses a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur amino acid metabolism characterised...

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Identifiers

PMID: 12686134
DOI: 10.1016/s1570-9639(03)00048-7

Genes

CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12686134-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Structural insights into mutations of cystathionine beta-synthase.PMID 12686134Read ↗

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