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Article

Specific pathways prevent duplication-mediated genome rearrangements.

Nature - 20 Aug 2009

Putnam Christopher D, Hayes Tikvah K, Kolodner Richard D

Abstract excerpt

We have investigated the ability of different regions of the left arm of Saccharomyces cerevisiae chromosome V to participate in the formation of gross chromosomal rearrangements (GCRs). We found that the 4.2-kilobase HXT13-DSF1 region sharing divergent homology with chromosomes IV, X and XIV, similar to mammalian segmental duplications, was 'at risk' for participating in duplication-mediated GCRs generated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19641493
DOI: 10.1038/nature08217
PMCID: PMC2785216

Genes

MRC1
MSH2
MSH6
RMI1
SLX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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