Article
Probing the Potential Role of Non-B DNA Structures at Yeast Meiosis-Specific DNA Double-Strand Breaks.
Biophysical journal - 23 May 2017
Kshirsagar Rucha, Khan Krishnendu, Joshi Mamata V, Hosur Ramakrishna V, Muniyappa K
Abstract excerpt
A plethora of evidence suggests that different types of DNA quadruplexes are widely present in the genome of all organisms. The existence of a growing number of proteins that selectively bind and/or process these structures underscores their biological relevance. Moreover, G-quadruplex DNA has been implicated in the alignment of four sister chromatids by forming parallel guanine quadruplexes during meiosis;...
Topics
- Circular Dichroism
- DNA Breaks, Double-Stranded
- DNA, Single-Stranded
- DNA-Binding Proteins
- DNA-Directed DNA Polymerase
- Escherichia coli
- G-Quadruplexes
- GC Rich Sequence
- Green Fluorescent Proteins
- Meiosis