Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons.

Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2012

English Christopher N, Vigers Alison J, Jones Kevin R

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a secreted protein important for development and function of neocortical circuitry. Although it is well established that BDNF contributes to the sculpting of dendrite structure and modulation of synapse strength, the range and directionality of BDNF sig...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Animals, Newborn
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Spines

Share to Gene Expression Regulation

Share to Genetic Loci

Share to Neurons

Share to Visual Cortex

Source

Open in PubMed Open full text

Identifiers

PMID: 23129644
DOI: 10.1073/pnas.1206492109
PMCID: PMC3511098

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23129644-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons.PMID 23129644Read ↗

The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease?Semantic proximity Read ↗

The Role of BDNF in the Development of Fear Learning.Semantic proximity Read ↗

The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.Semantic proximity Read ↗

Brain-derived neurotrophic factor as a model system for examining gene by environment interactions across development.Semantic proximity Read ↗

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations.Semantic proximity Read ↗

Distinct role of 5′UTR sequences in dendritic trafficking of BDNF mRNA: additional mechanisms for the BDNF splice variants spatial codeSemantic proximity Read ↗

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival.Semantic proximity Read ↗

A common human brain-derived neurotrophic factor polymorphism leads to sustained depression of excitatory synaptic transmission by isoflurane in hippocampusSemantic proximity Read ↗

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.Semantic proximity Read ↗

Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype.Semantic proximity Read ↗

Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.Semantic proximity Read ↗

Anterograde transport of brain-derived neurotrophic factor and its role in the brain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.