Anterograde transport of brain-derived neurotrophic factor and its role in the brain.

doi:10.1038/39885

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Article

Anterograde transport of brain-derived neurotrophic factor and its role in the brain.

Nature - 23 Oct 1997

Altar C A, Cai N, Bliven T, Juhasz M, Conner J M, Acheson A L, Lindsay R M, Wiegand S J

Abstract excerpt

The role of neurotrophins as target-derived proteins that promote neuron survival following their retrograde transport from the terminals to the cell bodies of neurons has been firmly established in the developing peripheral nervous system. However, neurotrophins appear to have more diverse functions, particularly in the adult central nervous system. Brain-derived neurotrophic factor (BDNF), for example, produces...

Topics

Animals
Axonal Transport
Brain
Brain-Derived Neurotrophic Factor
Denervation
Humans
Immunohistochemistry
Male
Mice
Mutation
Neostriatum
Neurons, Afferent
Parvalbumins
RNA, Messenger
Rats
Rats, Sprague-Dawley

Source

Open in PubMed

Identifiers

PMID: 9349818
DOI: 10.1038/39885

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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