Article
Analysis of E-Selectin S128R gene polymorphism in pancreatic cancer.
Journal of surgical oncology - 1 Nov 2010
Panoussopoulos George S, Theodoropoulos George, Michalopoulos Nikolaos V, Gazouli Maria, Flessas John, Taka Stela, Stamopoulos Paraskevas, Manouras Andreas, Zografos George C
Abstract excerpt
BACKGROUND: E-selectin, an intercellular adhesion molecule that plays important roles in metastasis of tumor cells, has a polymorphism in exon 4 that results in the substitution of a serine by an arginine within the extracellular domain of the receptor, which increases its affinity for ligands. No evidence exist on the role of E-selectin polymorphism in pancreatic cancer. METHODS: Eighty pancreatic cancer...
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