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Article

E-selectin gene S128R polymorphism is associated with poor prognosis in patients with stage II or III colorectal cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2009

Hebbar Mohamed, Adenis Antoine, Révillion Françoise, Duhamel Alain, Romano Olivier, Truant Stéphanie, Libersa Christian, Giraud Claire, Triboulet Jean-Pierre, Pruvot François-René, Peyrat Jean-Philippe

Abstract excerpt

Some host-related factors may predict the risk of metastasis after surgery of colorectal cancer (CRC). The endothelial adhesion molecule E-selectin is implicated in the metastatic spread of CRC. We postulated that some polymorphisms within the E-selectin gene, especially the S128R polymorphism, may increase the risk of metastases by facilitating adhesion of tumour cells to the endothelium. We collected blood...

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PMID: 19361981
DOI: 10.1016/j.ejca.2009.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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