Article
E-Selectin S128R gene polymorphism in gastric cancer.
The International journal of biological markers - 23 Apr 2013
Liarmakopoulos Emmanouil, Gazouli Maria, Aravantinos Gerasimos, Theodoropoulos George, Rizos Spyros, Vaiopoulou Anna, Kouraklis Gregory, Nikiteas Nikolaos
Abstract excerpt
BACKGROUND: E-selectin is an adhesion molecule expressed on activated endothelial cells. E-selectin plays an important role in the process of inflammation and is also involved in the mechanism of cancer metastasis regulating the adhesion of circulating cancer cells to the blood vessels. The aim of our study was to determine whether an association exists between its most common gene polymorphism, S128R, and...
Topics
- Aged
- Amino Acid Substitution
- Case-Control Studies
- E-Selectin
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Kaplan-Meier Estimate
