Article
Genetic analysis of polymorphisms in dopamine receptor and transporter genes for association with smoking among cancer patients.
European addiction research - 1 Jan 2013
Gordiev Marat, Engstrom Paul F, Khasanov Rustem, Moroshek Anton, Sitdikov Rustem, Dgavoronkov Vladamir, Schnoll Robert A
Abstract excerpt
BACKGROUND: Smoking among Russian cancer patients may be related to variations in the DRD2/ANKK1 (Taq1), DRD4 (exon III VNTR), and SLC6A3 genes. METHODS: Seven hundred fifty patients provided smoking history and DNA. RESULTS: Current smokers were more likely to be DRD2 A2 allele carriers versus nonsmokers (former/never smokers; 69 vs. 56%; OR = 1.69; 95% CI 1.13-2.53, p = 0.01) and former smokers (69 vs. 59%; OR...
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