Article
Association and family studies of DRD2 gene polymorphisms in alcohol dependence syndrome.
Postepy higieny i medycyny doswiadczalnej (Online) - 6 Nov 2014
Małecka Iwona, Jasiewicz Andrzej, Suchanecka Aleksandra, Samochowiec Jerzy, Grzywacz Anna
Abstract excerpt
INTRODUCTION: The human dopamine receptor 2 gene DRD2 plays a central role in susceptibility to Alcohol Dependence Syndrome (ADS). The aim of this study was to evaluate 3 single nucleotide polymorphisms: D2 (rs1076560), Tag1D (rs1800498), Tag1B (rs1079597) located in dopamine receptor 2 DRD2 gene and its role in alcohol dependence. MATERIAL AND METHODS: DNA was provided from alcohol dependent (AD) patients...
Topics
- Adult
- Alcoholism
- Alleles
- Case-Control Studies
- DNA
- Disease Susceptibility
- Family
- Fathers
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Mothers
- Poland
- Polymorphism, Single Nucleotide
- Receptors, Dopamine D2
