Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population.

BMC medical genetics - 17 Sept 2009

Sieminska Alicja, Buczkowski Krzysztof, Jassem Ewa, Niedoszytko Marek, Tkacz Ewa

Abstract excerpt

BACKGROUND: Polymorphisms in dopaminergic genes may influence cigarette smoking by their potential impact on dopamine reward pathway function. A1 allele of DRD2 gene is associated with a reduced dopamine D2 receptor density, and it has been hypothesised that A1 carriers are more vulnerable to smoking. In turn, the 9-repeat allele of dopamine transporter gene (SLC6A3) has been associated with a substantial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

Share to Heterozygote

Share to Poland

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D2

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 19761593
DOI: 10.1186/1471-2350-10-92
PMCID: PMC2758863

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population.PMID 19761593Read ↗

Evidence suggesting the role of specific genetic factors in cigarette smoking.Semantic proximity Read ↗

Smoking Genes: A Case-Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort.Semantic proximity Read ↗

Polymorphisms in HTR2A and DRD4 Predispose to Smoking and Smoking Quantity.Semantic proximity Read ↗

Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population.Semantic proximity Read ↗

Dopamine receptor genes (DRD2, DRD3 and DRD4) and gene-gene interactions associated with smoking-related behaviors.Semantic proximity Read ↗

Effects of Interaction Between Dopamine D2 Receptor and Monoamine Oxidase A Genes on Smoking Status in Young Men.Semantic proximity Read ↗

Dopamine-related genes and spontaneous smoking cessation in ever-heavy smokers.Semantic proximity Read ↗

The association of dopamine pathway gene score, nicotine dependence and smoking cessation in a rural male population of Shandong, China.Semantic proximity Read ↗

Distinct haplogenotypes of the dopamine D2 receptor gene are associated with non-smoking behaviour and daily cigarette consumption.Semantic proximity Read ↗

Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents.Semantic proximity Read ↗

Smoking, genes encoding dopamine pathway and risk for Parkinson's disease.Semantic proximity Read ↗

Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.