Article
Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.
Journal of the National Cancer Institute - 4 Mar 1998
Spitz M R, Shi H, Yang F, Hudmon K S, Jiang H, Chamberlain R M, Amos C I, Wan Y, Cinciripini P, Hong W K, Wu X
Abstract excerpt
BACKGROUND: Interindividual differences in the structure and expression of the dopamine receptor genes affect dopamine availability and may be the genetic basis for variation in vulnerability to tobacco smoking. In this study, prevalences of polymorphisms in the TaqIA allele (A1 and A2) and the TaqIB allele (B1 and B2) of the D2 dopamine receptor gene in 157 lung cancer case patients and 126 control subjects were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
