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Article

Polymorphisms of dopamine receptor/transporter genes and risk of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2007

Campa Daniele, Zienolddiny Shanbeh, Lind Helge, Ryberg David, Skaug Vidar, Canzian Federico, Haugen Aage

Abstract excerpt

BACKGROUND: The dopaminergic pathway may be of interest in assessing risk of non-small cell lung cancer (NSCLC). Dopamine receptors are expressed in alveolar epithelial cells and human lung tumours, and dopamine inhibits both cell proliferation in vitro and growth of lung tumour xenografts in nude mice. Moreover, dopamine selectively inhibits the vascular permeability and angiogenic activity of vascular...

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Source

Identifiers

PMID: 17175058
DOI: 10.1016/j.lungcan.2006.11.007

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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