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Article

TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.

Biological psychiatry - 1 Apr 2011

Ducci Francesca, Kaakinen Marika, Pouta Anneli, Hartikainen Anna-Liisa, Veijola Juha, Isohanni Matti, Charoen Pimphen, Coin Lachlan, Hoggart Clive, Ekelund Jesper, Peltonen Leena, Freimer Nelson, Elliott Paul, Schumann Gunter, Järvelin Marjo-Riitta

Abstract excerpt

BACKGROUND: CHRNA5-CHRNA3-CHRNB4 and TTC12-ANKK1-DRD2 gene-clusters influence smoking behavior. Our aim was to test developmental changes in their effects as well as the interplays between them and with nongenetic factors. METHODS: Participants included 4762 subjects from a general population-based, prospective Northern Finland 1966 Birth Cohort (NFBC 1966). Smoking behavior was collected at age 14 and 31 years....

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Source

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Identifiers

PMID: 21168125
DOI: 10.1016/j.biopsych.2010.09.055
PMCID: PMC3058144

Genes

CHRNA3
CHRNA5
CHRNB4
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.PMID 21168125Read ↗

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