Article
The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Lee So Hee, Lee Bun-Hee, Lee Jun-Seok, Chai Young Gyu, Choi Mi Ran, Han Dal Mu Ri, Ji Hong, Jang Gyeong-Ho, Shin Hye Eun, Choi Ihn Geun
Abstract excerpt
AIMS: Dopamine receptors are associated with reward and dependence towards alcohol. The polymorphisms of dopamine D2 receptor (DRD2) genes have been reported to be involved in susceptibility to alcoholism. Therefore, we investigated the association of three single-nucleotide polymorphisms (SNPs) in DRD2 and ankyrin repeat and kinase domain containing one (ANKK1) genes with alcohol dependence in Korean subjects,...
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