Article
DRD2 genetic variation in relation to smoking and obesity in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Pharmacogenetics and genomics - 1 Dec 2006
Morton Lindsay M, Wang Sophia S, Bergen Andrew W, Chatterjee Nilanjan, Kvale Paul, Welch Robert, Yeager Meredith, Hayes Richard B, Chanock Stephen J, Caporaso Neil E
Abstract excerpt
OBJECTIVES: Cigarette smoking is the leading cause of morbidity and mortality worldwide. We investigated the association between smoking behavior and genetic variations in the D2 dopamine receptor (DRD2), which mediates nicotine dependence. To assess the specificity of genetic effects, we also investigated other reward-motivated characteristics (obesity, alcohol consumption). METHODS: Four single nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.