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Article

Aberrant Alternative Splicing Events in Parkinson's Disease

1 Apr 2013

Abstract excerpt

Alternative splicing (AS) using a sole gene to express multiple transcripts with diverse protein coding sequences and/or RNA regulatory elements raises genomic complexities. In the nervous system, several thousand AS events play important roles in ion transportation, receptor recognition, neurotransmission, memory, and learning. Not surprisingly, AS influences human physiology, development, and disease. Many...

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PMID: 23127794
DOI: 10.3727/096368912x655154

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