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Article

Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene

1 Jun 2014

Abstract excerpt

The completion of the Human Genome Project aroused renewed interest in alternative splicing, an efficient and widespread mechanism that generates multiple protein isoforms from individual genes. Although our knowledge about alternative splicing is growing exponentially, its real impact on cellular life is still to be clarified. Connecting all splicing features (genes, splice transcripts, isoforms, and relative...

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PMID: 24955028
DOI: 10.2174/1389202915666140426003342

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