Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of candidate genes for Parkinson's disease through blood transcriptome analysis in LRRK2-G2019S carriers, idiopathic cases, and controls.

Neurobiology of aging - 1 Feb 2015

Infante Jon, Prieto Carlos, Sierra María, Sánchez-Juan Pascual, González-Aramburu Isabel, Sánchez-Quintana Coro, Berciano José, Combarros Onofre, Sainz Jesús

Abstract excerpt

The commonest known cause of Parkinson's disease (PD) is the G2019S mutation of the LRRK2 gene, but this mutation is not sufficient for causing PD, and many carriers of the mutation never develop PD symptoms during life. Differences at the expression level of certain genes, resulting from either genetic variations or environmental interactions, might be one of the mechanisms underlying differential risks for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Association Studies
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Parkinson Disease

Share to Protein Serine-Threonine Kinases

Share to RNA, Messenger

Share to Sequence Analysis, RNA

Source

Identifiers

PMID: 25475535
DOI: 10.1016/j.neurobiolaging.2014.10.039

Genes

ADARB2
CEACAM6
CNTNAP2
DRAXIN
FCER2
HBG1
NCAPG2
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of candidate genes for Parkinson's disease through blood transcriptome analysis in LRRK2-G2019S carriers, idiopathic cases, and controls.PMID 25475535Read ↗

Comparative blood transcriptome analysis in idiopathic and LRRK2 G2019S-associated Parkinson's disease.Semantic proximity Read ↗

Plasma acellular transcriptome contains Parkinson’s disease signatures that can inform clinical diagnosisSemantic proximity Read ↗

Elucidate biomarkers and the molecular pathways associated with genetic variants that contribute to the etiology of Parkinson's disease.Semantic proximity Read ↗

Pathogenic genes associated with Parkinson’s disease: molecular mechanism overviewSemantic proximity Read ↗

Large-scale Rare Variant Burden Testing in Parkinson’s Disease Identifies Novel Associations with Genes Involved in Neuro-inflammationSemantic proximity Read ↗

Whole-genome sequencing of 197 cases with Parkinson’s Disease reveals novel pathogenic variants in the Indian populationSemantic proximity Read ↗

Novel Parkinson’s Disease Genetic Risk Factors Within and Across European PopulationsSemantic proximity Read ↗

Leveraging blood RNA expression to understand Parkinson’s disease heterogeneity and progressionSemantic proximity Read ↗

Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation.Semantic proximity Read ↗

Parkinson’s Disease Genetic Risk Evaluation in Microglia Highlights Autophagy and Lysosomal GenesSemantic proximity Read ↗

Deciphering the Genetic Architecture of Parkinson’s Disease in IndiaSemantic proximity Read ↗

Genetic basis of Parkinson's disease: inheritance, penetrance, and expressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.