Article
Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses.
BMC genomics - 5 Nov 2012
Lionikas Arimantas, Meharg Caroline, Derry Jonathan Mj, Ratkevicius Aivaras, Carroll Andrew M, Vandenbergh David J, Blizard David A
Abstract excerpt
BACKGROUND: We have recently identified a number of Quantitative Trait Loci (QTL) contributing to the 2-fold muscle weight difference between the LG/J and SM/J mouse strains and refined their confidence intervals. To facilitate nomination of the candidate genes responsible for these differences we examined the transcriptome of the tibialis anterior (TA) muscle of each strain by RNA-Seq. RESULTS: 13,726 genes were...
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