Article
Expression quantitative trait loci: replication, tissue- and sex-specificity in mice.
Genetics - 1 Jul 2010
van Nas Atila, Ingram-Drake Leslie, Sinsheimer Janet S, Wang Susanna S, Schadt Eric E, Drake Thomas, Lusis Aldons J
Abstract excerpt
By treating the transcript abundance as a quantitative trait, gene expression can be mapped to local or distant genomic regions relative to the gene encoding the transcript. Local expression quantitative trait loci (eQTL) generally act in cis (that is, control the expression of only the contiguou...
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