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Article

Integrating genetic and network analysis to characterize genes related to mouse weight.

PLoS genetics - 18 Aug 2006

Ghazalpour Anatole, Doss Sudheer, Zhang Bin, Wang Susanna, Plaisier Christopher, Castellanos Ruth, Brozell Alec, Schadt Eric E, Drake Thomas A, Lusis Aldons J, Horvath Steve

Abstract excerpt

Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker data from an F2 mouse intercross to examine the large-scale organization of the gene co-expression network in liver, and annotate several gene modules in terms of 22 physiological traits. We identify chromosomal loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16934000
DOI: 10.1371/journal.pgen.0020130
PMCID: PMC1550283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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