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Article

Metabolism of 7-ethoxycoumarin, safrole, flavanone and hydroxyflavanone by cytochrome P450 2A6 variants.

Biopharmaceutics & drug disposition - 1 Mar 2013

Uno Tomohide, Obe Yuichiro, Ogura Chika, Goto Tatsushi, Yamamoto Kohei, Nakamura Masahiko, Kanamaru Kengo, Yamagata Hiroshi, Imaishi Hiromasa

Abstract excerpt

CYP 2A6 is a human enzyme that metabolizes many xenobiotics including coumarin, indole, nicotine and carcinogenic nitrosamines. The gene for CYP2A6 is polymorphic. There are few data available to clarify the relationship between P450 genetic variants and the metabolism of materials in food. The C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23112005
DOI: 10.1002/bdd.1825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23112005-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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