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Article

Functional characterization of cytochrome P450 2B6 allelic variants.

Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2003

Jinno Hideto, Tanaka-Kagawa Toshiko, Ohno Akiko, Makino Yuko, Matsushima Erika, Hanioka Nobumitsu, Ando Masanori

Abstract excerpt

Cytochrome P450 (P450) 2B6 is a hepatic enzyme of potential importance for the metabolism of clinically used drugs and environmental or abused toxicants. Genetic polymorphisms of CYP2B6 (CYP2B6*2, CYP2B6*3, CYP2B6*4, CYP2B6*5, CYP2B6*6 and CYP2B6*7; wild-type, CYP2B6*1) were found previously in white and Japanese populations. In the present study, the goal was to investigate the effects of amino acid...

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Identifiers

PMID: 12642465
DOI: 10.1124/dmd.31.4.398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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