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Article

Functional characterization of 26 CYP2B6 allelic variants (CYP2B6.2-CYP2B6.28, except CYP2B6.22).

Pharmacogenetics and genomics - 1 Jul 2010

Watanabe Takashi, Sakuyama Kanako, Sasaki Takamitsu, Ishii Yuya, Ishikawa Masaaki, Hirasawa Noriyasu, Hiratsuka Masahiro

Abstract excerpt

Cytochrome P450 2B6 (CYP2B6) is a potentially important enzyme for the metabolism of clinical drugs, and it exhibits genetic polymorphism. Thus far, 29 allelic variants of CYP2B6 (CYP2B6*1-CYP2B6*29) have been identified. This study aimed to investigate whether 26 of the variant alleles of CYP2B6 (CYP2B6*2-CYP2B6*21 and CYP2B6*23-CYP2B6*28) affect its kinetics in the metabolism of...

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PMID: 20517174
DOI: 10.1097/FPC.0b013e32833bba0e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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