Article
Association between nicotine metabolism and CYP2A6*1 and CYP2A6*4 genotypes in an Iranian population.
DNA and cell biology - 1 Jul 2010
Heravi Reza Entezari, Ramezani Mohammad, Behravan Javad
Abstract excerpt
The cytochrome P450 (CYP) family is the principal enzyme system involved in the metabolism of xenobiotics and endogenous compounds. Among this family, CYP2A6 is one of the most important enzymes for metabolism of nicotine. In this study, the linkage of CYP2A6*1 and CYP2A6*4 genotypes with nicotine metabolism was investigated. A single polymerase chain reaction-restriction fragment length polymorphism was used to...
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