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Article

The Hydra FGFR, Kringelchen, partially replaces the Drosophila Heartless FGFR.

Development genes and evolution - 1 May 2013

Rudolf Anja, Hübinger Christine, Hüsken Katrin, Vogt Angelika, Rebscher Nicole, Onel Susanne-Filiz, Renkawitz-Pohl Renate, Hassel Monika

Abstract excerpt

Fibroblast growth factor receptors (FGFR) are highly conserved receptor tyrosine kinases, and evolved early in metazoan evolution. In order to investigate their functional conservation, we asked whether the Kringelchen FGFR in the freshwater polyp Hydra vulgaris, is able to functionally replace FGFR in fly embryos. In Drosophila, two endogenous FGFR, Breathless (Btl) and Heartless (Htl), ensure formation of the...

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PMID: 23111653
DOI: 10.1007/s00427-012-0424-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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