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Article

Differential and overlapping functions of two closely related Drosophila FGF8-like growth factors in mesoderm development.

Development (Cambridge, England) - 1 Jul 2009

Klingseisen Anna, Clark Ivan B N, Gryzik Tanja, Müller H-Arno J

Abstract excerpt

Thisbe (Ths) and Pyramus (Pyr), two closely related Drosophila homologues of the vertebrate fibroblast growth factor (FGF) 8/17/18 subfamily, are ligands for the FGF receptor Heartless (Htl). Both ligands are required for mesoderm development, but their differential expression patterns suggest distinct functions during development. We generated single mutants and found that ths or pyr loss-of-function mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19515694
DOI: 10.1242/dev.035451
PMCID: PMC2729350

Genes

FGF8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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