Article
Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Aug 2015
Zhuang Lei, Bluteau Gilles, Trueb Beat
Abstract excerpt
FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family. Similar to the classical receptors FGFR1-FGFR4, it contains three extracellular Ig-like domains and a single transmembrane domain. However, it lacks the intracellular tyrosine kinase domain that would be required for signal transduction, but instead contains a short intracellular tail with a peculiar histidine-rich motif. This motif has...
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