Fibroblast growth factor signaling in Caenorhabditis elegans.

doi:10.1002/bies.10007

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Article

Fibroblast growth factor signaling in Caenorhabditis elegans.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 2001

Borland C Z, Schutzman J L, Stern M J

Abstract excerpt

Growth factor receptor tyrosine kinases (RTKs), such as the fibroblast growth factor receptor (FGFR), play a major role in how cells communicate with their environment. FGFR signaling is crucial for normal development, and its misregulation in humans has been linked to developmental abnormalities and cancer. The precise molecular mechanisms by which FGFRs transduce extracellular signals to effect specific...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Fibroblast Growth Factors
Genetic Testing
Helminth Proteins
Humans
Ligands
Phenotype
Receptors, Fibroblast Growth Factor
Signal Transduction
ras Proteins

Source

Open in PubMed

Identifiers

PMID: 11746231
DOI: 10.1002/bies.10007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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