Article
FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation.
Development (Cambridge, England) - 1 Mar 2009
Kadam Snehalata, McMahon Amy, Tzou Phoebe, Stathopoulos Angelike
Abstract excerpt
Fibroblast growth factor (FGF) signaling controls a vast array of biological processes including cell differentiation and migration, wound healing and malignancy. In vertebrates, FGF signaling is complex, with over 100 predicted FGF ligand-receptor combinations. Drosophila melanogaster presents a simpler model system in which to study FGF signaling, with only three ligands and two FGF receptors (FGFRs)...
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