Article
Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships.
Developmental biology - 1 Apr 2007
Yokoi Hayato, Shimada Atsuko, Carl Matthias, Takashima Shigeo, Kobayashi Daisuke, Narita Takanori, Jindo Tomoko, Kimura Tetsuaki, Kitagawa Tadao, Kage Takahiro, Sawada Atsushi, Naruse Kiyoshi, Asakawa Shuichi, Shimizu Nobuyoshi, Mitani Hiroshi, Shima Akihiro, Tsutsumi Makiko, Hori Hiroshi, Wittbrodt Joachim, Saga Yumiko, Ishikawa Yuji, Araki Kazuo, Takeda Hiroyuki
Abstract excerpt
Medaka (Oryzias latipes) is a small freshwater teleost that provides an excellent developmental genetic model complementary to zebrafish. Our recent mutagenesis screening using medaka identified headfish (hdf) which is characterized by the absence of trunk and tail structures with nearly normal head including the midbrain-hindbrain boundary (MHB). Positional-candidate cloning revealed that the hdf mutation causes...
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