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Article

Association of interleukin-17F (rs763780) single nucleotide polymorphism with multiple sclerosis and optic neuritis.

Scientific reports - 13 Jun 2024

Salah Shereen, Sadeq Yousra I, Mosaad Youssef M, Elmenshawi Ibrahim E H, Tawhid Ziyad M E

Abstract excerpt

IL-17F single nucleotide polymorphism (SNP) can affect IL-17F expression and activity and this can lead to the increased susceptibility to several autoimmune diseases. The aim was to investigate the association of IL-17F (rs763780) SNP with the development of multiple sclerosis (MS) in a cohort of Egyptian patients and to evaluate the effect of this polymorphism on the disease course. IL-17F (rs763780) gene...

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Identifiers

PMID: 38871733
DOI: 10.1038/s41598-024-62736-2
PMCID: PMC11176185

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