Article
Association study between IL-17A and IL-17F gene polymorphism and myasthenia gravis in Chinese patients.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Jan 2016
Yue Yao-Xian, Hong Yu, Xie Yanchen, Hao Hong-Jun, Sui Yi, Gu Chuan-Kai, Zhang Xu, Gao Xiang, Tang Tian-Ping, Zhang Xian-Jun, Wang Qi, Li Hai-Feng
Abstract excerpt
Alleles of IL-17A and IL-17F genes were reported to be associated with many inflammatory and autoimmune disorders in Asian patients. Serum level and mRNA of IL-17A in peripheral blood mononuclear cells were reported to be significantly higher in MG patients than in healthy controls. In experimental autoimmune myasthenia gravis (EAMG) animals, IL-17 may have effects on the severity of MG. This study investigated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
