Article
Screening for melanocortin-4 receptor mutations in a cohort of Belgian morbidly obese adults and children.
International journal of obesity (2005) - 1 Feb 2006
Beckers S, Mertens I, Peeters A, Van Gaal L, Van Hul W
Abstract excerpt
OBJECTIVE: To investigate whether pathogenic melanocortin-4 receptor (MC4R) mutations are a common cause of obesity in Belgium. DESIGN: Cross-sectional mutation analysis. SUBJECTS: In total, 95 morbidly obese adults (mean age 44.02+/-11.35 years; mean BMI 47.87+/-4.17 kg/m2 and 123 obese children and adolescents were screened for mutations in MC4R (mean age 16.56+/-2.58 years; BMI>95th percentile for age and sex;...
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