Article
A functional promoter polymorphism -607G>C of WNT10B is associated with abdominal fat in Korean female subjects.
The Journal of nutritional biochemistry - 1 Mar 2011
Kim Il Chul, Cha Min Ho, Kim Dong Min, Lee Haeyong, Moon Jin Seok, Choi Sun Mi, Kim Kil Soo, Yoon Yoosik
Abstract excerpt
WNT10B has been implicated as a potential regulator of adipogenesis in cellular and animal models of obesity. In this study, we attempted to characterize the associations between common genetic polymorphisms of WNT10B and fat accumulation in a sample of 1029 Korean female subjects. Direct sequencing of genomic DNAs of 45 subjects identified six common single-nucleotide polymorphisms (SNPs) of WNT10B, which were...
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