Article
Genetic association between WNT10B polymorphisms and obesity in a Belgian case-control population is restricted to males.
Molecular genetics and metabolism - 1 Mar 2012
Van Camp J K, Beckers S, Zegers D, Verrijken A, Van Gaal L F, Van Hul W
Abstract excerpt
The Wnt pathway has been shown to play an important role in maintenance of stem cells and cell fate decisions in embryonic and adult stem cell populations. Activation of the Wnt pathway in mesenchymal stem cells and 3 T3-L1 cells inhibits adipogenesis and can lead to osteoblastogenesis. To evaluate the role of the Wnt pathway in adipogenesis and obesity further, we analysed the genetic association between...
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