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Article

Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy.

Journal of hematology & oncology - 26 Oct 2012

Rachagani Satyanarayana, Torres María P, Kumar Sushil, Haridas Dhanya, Baine Michael, Macha Muzafar A, Kaur Sukhwinder, Ponnusamy Moorthy P, Dey Parama, Seshacharyulu Parthasarathy, Johansson Sonny L, Jain Maneesh, Wagner Kay-Uwe, Batra Surinder K

Abstract excerpt

BACKGROUND: Pancreatic cancer (PC) is a lethal malignancy primarily driven by activated Kras mutations and characterized by the deregulation of several genes including mucins. Previous studies on mucins have identified their significant role in both benign and malignant human diseases including PC progression and metastasis. However, the initiation of MUC expression during PC remains unknown because of lack of...

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Source

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Identifiers

PMID: 23102107
DOI: 10.1186/1756-8722-5-68
PMCID: PMC3511181

Genes

CXCL1
CXCL2
MUC1
MUC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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