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Article

The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.

Seminars in cancer biology - 1 Jun 2001

Bardeesy N, Sharpless N E, DePinho R A, Merlino G

Abstract excerpt

Pancreatic cancer is among the leading causes of cancer death. Although a genetic profile for pancreatic cancer is emerging, many biological aspects of this disease are poorly understood. Indeed, fundamental questions regarding progenitor cell lineages, host stromal milieu, and the role of specific genetic alterations in tumor progression remain unresolved. A mouse model engineered with signature mutations would...

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Identifiers

PMID: 11407945
DOI: 10.1006/scbi.2000.0371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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