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Article

Aneurysm formation in proinflammatory, transgenic haptoglobin 2-2 mice.

Neurosurgery - 1 Jan 2013

Ruzevick Jacob, Jackson Christopher, Pradilla Gustavo, Garzon-Muvdi Tomas, Tamargo Rafael J

Abstract excerpt

BACKGROUND: Inflammation and macrophages in particular are believed to play a role in aneurysm formation. The haptoglobin (Hp) 2-2 genotype is associated with a proinflammatory state. OBJECTIVE: To investigate the role of inflammation in the formation of aneurysms using a murine model of aneurysm formation in transgenic, proinflammatory Hp2-2 mice and wild-type Hp1-1 mice. METHODS: Carotid artery aneurysms were...

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Source

Identifiers

PMID: 23096414
DOI: 10.1227/NEU.0b013e318276b306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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