Article
Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.
International journal of experimental pathology - 1 Dec 1999
Coutard M
Abstract excerpt
The Blotchy mouse is characterized by an X-linked inherited disorder of connective tissue synthesis. The susceptibility to aneurysm formation in the cerebral arteries of the circle of Willis was compared in female heterozygous 'Blotchy' and control mice subjected to unilateral carotid artery ligation either alone or associated with hypertension. Cerebral aneurysms developed only in hypertensive Blotchy mice (6/31...
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