Article
Haptoglobin 2-1 phenotype predicts rapid growth of abdominal aortic aneurysms.
Journal of vascular surgery - 1 Sept 2010
Wiernicki Ireneusz, Safranow Krzysztof, Baranowska-Bosiacka Irena, Piatek Jaroslaw, Gutowski Piotr
Abstract excerpt
BACKGROUND: Haptoglobin (Hp) polymorphism is associated with the prevalence and clinical evolution of many inflammatory diseases and atherosclerosis. Circulating neutrophils and neutrophil-associated proteases are an important initial component of experimental abdominal aortic aneurysm (AAA) formation. Elastase and C-reactive protein (CRP) levels are elevated in patients with AAAs. This study assessed the...
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