Article
M1 macrophages are required for murine cerebral aneurysm formation.
Journal of neurointerventional surgery - 1 Jan 2018
Nowicki Kamil W, Hosaka Koji, Walch Frank J, Scott Edward W, Hoh Brian L
Abstract excerpt
INTRODUCTION: Macrophages and neutrophils have been separately implicated in cerebral aneurysm formation. The interactions between different myeloid subsets and the contributions of macrophage phenotypes in these lesions over time are not known. The purpose of the study was to examine macrophage phenotypic changes in cerebral aneurysms. METHODS: We induced aneurysm formation in C57BL/6 mice and quantified...
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