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Article

Haptoglobin Genotype Affects Inflammation after Aneurysmal Subarachnoid Hemorrhage.

Current neurovascular research - 1 Jan 2020

Gusdon Aaron M, Savarraj Jude, Zhu Liang, Pandit Peeyush K Thankamani, Doré Sylvain, McBride Devin W, Choi HuiMahn A, Blackburn Spiros L

Abstract excerpt

BACKGROUND: Haptoglobin (Hp) binds to and facilitates clearance of heme. Compared with HP 1-1 and 1-2 genotypes, HP 2-2 has a weaker binding affinity and has been linked with increased inflammation and vasospasm after aneurysmal subarachnoid hemorrhage (SAH). OBJECTIVE: This study aims to assess levels of inflammatory cytokines in the context of different HP genotypes. METHODS: Patients were enrolled among those...

Topics

Adult
Aged
Biomarkers
Cytokines
Female
Genotype
Haptoglobins
Humans
Inflammation
Male
Middle Aged
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retrospective Studies

Subarachnoid Hemorrhage

Source

Identifiers

PMID: 33319684
DOI: 10.2174/1567202617666201214104623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-33319684-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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