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Article

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.

Developmental cell - 25 Nov 2013

Simó Sergi, Cooper Jonathan A

Abstract excerpt

Morphogenesis requires the proper migration and positioning of different cell types in the embryo. Much more is known about how cells start and guide their migrations than about how they stop when they reach their destinations. Here we provide evidence that Rbx2, a subunit of the Cullin 5-RING E3 ubiquitin ligase (CRL5) complex, stops neocortical projection neurons at their target layers. Rbx2 mutation causes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24210661
DOI: 10.1016/j.devcel.2013.09.022
PMCID: PMC3851519

Genes

SOCS7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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